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"NSAID Toxicity"
Although it can be hard to see your pet in any discomfort, it is not advised to give any sort of pain medication to a pet without first consulting a veterinarian. Not only are there drug interactions and dosages to keep track of, certain types of pain medications can be toxic to certain species. Cats are highly sensitive to acetominophen (Tylenol) and should never be given the drug. Ibuprofen (Advil) has a very narrow therapeutic index and if overdosed, can cause liver and kidney failure. Any nonsteroidal anti-inflammatory drug (aspirin, Tylenol, Advil, Alleve, etc) can have side effects to the gastrointestinal tract, kidneys, or liver and should never be used except under the direct supervision of a veterinarian. Veterinary products (Rimadyl, Deramaxx, Previcox, and Metacam) have been carefully studied in cats and dogs and are usually better options. They may provide more potent pain relief with less side effects. However, no drug is completely benign and side effects have been seen at a range of doses, especially if given certain types of medications It is important to let your veterinarian know if you are giving any over the counter medications or if you are giving any steroids (Prednisone, Prednisolone, Triamcinolone, etc) or if your pet has a history of any liver or kidney issues.
In the case of an acute overdose, (greater than 3x the recommended dose), it is important to contact a veterinarian as soon as possible. If the medication is recently ingested, emesis (vomiting) can be initiated to prevent absorption and activated charcoal can be given to bind the drug in the gastrointestinal tract. In more severe cases, bloodwork may be done and fluid support be given to support the organs and facilitate the excretion of the drug. In any case, a veterinarian should be consulted as to the best course of action for your pet. Keep in mind that flavored tablets such as Rimadyl and Deramaxx are often palatable to pets and should not be left out or on counters where dogs can reach them.
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